Combine ground bison, egg, cayenne, celery onion and crackers in a bowl.
Form mixture into 4 patties.
Brown bison patties on both sides.
Place the bison patties in a shallow baking dish. Then mix together the mushroom soup and water and pour the mixture over the bison patties.
Cover and bake in the oven for 30 minutes at 350 degrees.
Serve with your favorite side dishes and enjoy!